Louisville thoroughly dominated Kentucky on Saturday, winning 41-14 in a game that featured four lead changes. The Cardinals controlled the scoreboard from the opening quarter, scoring 7 points in the first quarter and 13 in the second to build an early advantage.

Kentucky's offense struggled for much of the contest, with quarterback Cutter Boley leading the Wildcats with 48 passing yards. Running back Jamarion Wilcox rushed for 66 yards in a limited offensive output. The Wildcats didn't score until the third quarter and managed just 7 points in each of the final two quarters.

Louisville's attack was far more efficient. Nate Kurisky led the receiving corps with 9 catches. The Cardinals scored touchdowns on multiple possessions, including a 58-yard touchdown run by Duke Watson in the second quarter and a 67-yard rushing touchdown by Isaac Brown in the fourth quarter.

The game went over the 49.5-point over/under line, with the final total of 55 points. Louisville covered the 4-point spread, securing a decisive victory in their regular-season finale.